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Alport Syndrome

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated

Renal DysfunctionHypertensionAnemiaHyperkalemiaUnstable ElectrolytesOptimize ElectrolytesProteinuriaDifficult AirwayAspirationEdemaImmunocompromiseAvoid Nephrotoxic DrugsSensorineural Hearing Loss

Pathophysiology

Alport syndrome, also called hereditary nephritis, is an inherited type IV collagen disorder. Mutations in COL4A3, COL4A4, or COL4A5 disrupt the alpha-3/alpha-4/alpha-5 collagen network that gives...

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