Bernard-Soulier Syndrome (BSS)

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated July 23, 2026

Blood Loss (Excessive)AnemiaCareful PositioningVideo LaryngoscopeAvoid Nasal InstrumentationAvoid Nephrotoxic DrugsAvoid NeuraxialPlatelet DysfunctionThrombocytopenia

Pathophysiology

Bernard-Soulier syndrome (BSS) is a rare inherited platelet disorder — roughly 1 per million, usually autosomal recessive — caused by mutations in GP1BA, GP1BB, or GP9, the genes encoding subunits of...

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Master Anesthesia

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Bernard-Soulier Syndrome (BSS)

Pathophysiology

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