Factor V Deficiency (Owren Disease, Parahemophilia)

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated July 22, 2026

Blood Loss (Excessive)AnemiaCareful PositioningAvoid Nasal InstrumentationFactor Replacement Required

Pathophysiology

Factor V — proaccelerin, or labile factor — is a non-enzymatic cofactor. The liver makes about 80% of it and platelet alpha granules the rest. Once thrombin or factor Xa activates it, factor Va joins...

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Master Anesthesia

Master Anesthesia

Factor V Deficiency (Owren Disease, Parahemophilia)

Pathophysiology

Read the full condition post with a free account