Granulomatosis with Polyangiitis (GPA)

Name: Granulomatosis with Polyangiitis (GPA): Anesthesia Implications
Creator: Master Anesthesia
Published: 2026-07-21T23:26:20.609Z

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated July 22, 2026

Risk factors

Difficult Airway
Renal Dysfunction
Hyperkalemia
Hypoxia
Anemia
Immunocompromise
Copious Secretions
Dry Eyes
Seizures
Unstable Electrolytes
Avoid Nasal Instrumentation
Pulmonary Hemorrhage

Pathophysiology

Granulomatosis with polyangiitis (GPA), formerly Wegener granulomatosis, is a necrotizing small- to medium-vessel vasculitis and the most common of the ANCA-associated vasculitides. Antibodies...

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