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Hereditary Hemorrhagic Telangiectasia (Osler-Weber-Rendu, HHT)

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated

AnemiaAvoid IV bubblesHypoxiaCyanosisDyspneaStroke RiskBlood Loss (Excessive)Pulmonary HypertensionAvoid Nasal InstrumentationRight-to-Left Shunt

Pathophysiology

Hereditary hemorrhagic telangiectasia (HHT), formerly Osler-Weber-Rendu, is an autosomal dominant disorder of vascular integrity. Mutations in ENG (HHT1, about 61%), ACVRL1/ALK1 (HHT2, about 37%), or...

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