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Ketamine Use Disorder

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated

Emergence DeliriumAvoid KetamineRenal DysfunctionHypertensionTachycardiaHypotensionSeizuresHyperthermiaAspirationCopious SecretionsArrhythmiasIncreased ICPUnstable ElectrolytesStroke RiskDelayed EmergencePlatelet DysfunctionRhabdomyolysis

Pathophysiology

Ketamine is a phencyclidine analogue and noncompetitive NMDA antagonist that also blocks sodium and potassium channels, antagonizes muscarinic and nicotinic acetylcholine receptors, activates D2 and...

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