Klinefelter Syndrome (KS)

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated July 23, 2026

Careful PositioningDysglycemiaAnterior Mediastinal MassThromboembolism Risk

Pathophysiology

Klinefelter syndrome ( KS ) is the presence of two or more X chromosomes in a phenotypic male, most often the 47,XXY karyotype (over 90% of cases). Mosaic karyotypes and higher-order aneuploidies...

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Klinefelter Syndrome (KS)

Pathophysiology

Read the full condition post with a free account