Certain anesthetics can influence ICP, with volatile anesthetics such as isoflurane or sevoflurane known to increase cerebral blood flow and potentially elevate ICP. In contrast, intravenous agents such as propofol or barbiturates may reduce cerebral metabolism and blood flow, leading to a decrease in ICP. Non-invasive monitoring can help assess the effects of anesthetic agents on ICP and guide the choice and titration of anesthetic depth to optimize both cerebral perfusion and patient safety. For instance, if non-invasive monitoring indicates a trend toward increasing ICP, the anesthesia provider might reduce the concentration of volatile anesthetics or deepen anesthesia with intravenous agents known to lower ICP.

Non-invasive ICP monitoring offers a window into the dynamic changes occurring in the intracranial compartment, and anesthesia providers must be able to recognize patterns that indicate impending neurological deterioration. Certain patterns of ICP elevation can have specific clinical implications, and timely recognition of these trends is key to preventing secondary brain injury.