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Macrocytic Megaloblastic Anemia

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated

AnemiaAvoid N2OHypoxiaTachycardiaDyspneaDysglycemiaPeripheral NeuropathyThrombocytopenia

Pathophysiology

Macrocytic megaloblastic anemia is anemia with an MCV over 100 fL caused by impaired DNA synthesis, most often from vitamin B12 (cobalamin) or folate deficiency. Both vitamins donate the one-carbon...

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