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Mixed Connective Tissue Disease (MCTD)

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated

Pulmonary HypertensionAvoid HypoxiaAvoid HypercarbiaAvoid AcidosisReduced Cardiac OutputAspirationFull StomachRSIDifficult AirwayAvoid HypothermiaArrhythmiasRenal DysfunctionProteinuriaAnemiaImmunocompromiseSkeletal Muscle WeaknessParalytic SensitivityCareful PositioningSkin FragilityDyspneaRight Ventricular FailureStress-Dose Steroid

Pathophysiology

Mixed connective tissue disease (MCTD) is a systemic autoimmune overlap syndrome defined by high-titer anti-U1-ribonucleoprotein (anti-U1-RNP) antibody plus features of at least two connective tissue...

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