From curare to sugammadex, this course walks you through how we got from early neuromuscular blockade to today’s precision reversal strategies—and what that means at the bedside. You’ll learn to distinguish cholinesterase inhibitors from cyclodextrin-based agents by mechanism and clinical application; anticipate and manage muscarinic side effects; and stay current on emerging NMBA/reversal pairs like chlorofumarates/L-cysteine and Calabadion, as well as practical reversal of opioids, benzodiazepines, local anesthetics, and anticoagulants to optimize recovery and patient safety.