This course explores the high-stakes interaction between CCBs and anesthetic drugs, with a practical focus for the cardiac patient in your OR. You’ll review how CCBs potentiate neuromuscular blockade, alter MAC, and amplify the negative inotropic and vasodilatory effects of halogenated agents like halothane, enflurane, and isoflurane—particularly in compromised myocardium. By the end, you’ll be able to anticipate hemodynamic instability, adjust anesthetic and NMB dosing, and apply evidence-based strategies (including calcium rescue and vigilant monitoring) to keep CCB-treated patients safe throughout anesthesia.