When anaphylaxis hits in the OR, seconds matter and ambiguity is deadly. This course equips you to rapidly recognize the full spectrum of perioperative hypersensitivity—from subtle hypotension and bronchospasm to full cardiovascular collapse—while knowing which agents are most likely to blame (antibiotics, NMBAs, chlorhexidine, dyes, and more). You’ll walk through practical, stepwise algorithms for adults and pediatrics, including precise epinephrine dosing, fluid resuscitation strategies, escalation for refractory cases, and post-event evaluation and referral. By the end, you’ll be ready to lead the room with confidence when perioperative anaphylaxis strikes.