This course breaks down the complex pathophysiology of PONV into practical, clinically relevant pathways you can act on at the bedside. You’ll review risk assessment tools, central and peripheral mechanisms, and compare major antiemetic classes—including 5-HT3 antagonists, steroids, anticholinergics, antidopaminergics, and adjuncts like TIVA and NSAIDs—so you can build smarter, multimodal prevention and rescue strategies that actually keep your patients comfortable and out of the PACU longer than necessary.