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Mucopolysaccharidosis (MPS)

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated

Difficult AirwayVideo LaryngoscopeC-spineCareful PositioningCopious SecretionsReactive AirwayBronchospasm riskPulmonary HypertensionIncreased ICPArrhythmiasReduced Cardiac OutputHypoxiaAvoid OpioidsLaryngospasm RiskObstructive Sleep ApneaTracheomalacia

Pathophysiology

The mucopolysaccharidoses are inherited lysosomal storage diseases caused by deficiency of one of eleven enzymes that degrade glycosaminoglycans (GAGs). Partially degraded GAGs accumulate...

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