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Myoglobinuric Acute Kidney Injury

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated

Renal DysfunctionHyperkalemiaUnstable ElectrolytesOptimize ElectrolytesOptimize HydrationHypovolemiaAvoid HypovolemiaDehydrationAvoid SuccinylcholineAvoid AcidosisArrhythmiasSeizuresSepsisMalignant Hyperthermia RiskCareful Positioning

Pathophysiology

Skeletal muscle breakdown — trauma and crush injury, immobilization, sepsis, cardiovascular surgery, seizures, alcohol, statins — leaks myoglobin, potassium, phosphate, uric acid, and creatine kinase...

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