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Myotonic Dystrophy (DM1, DM2)

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated

Avoid SuccinylcholineArrhythmiasBradycardiaSkeletal Muscle WeaknessParalytic SensitivityDelayed EmergenceAvoid HypothermiaAspirationAvoid OpioidsAvoid Neostigmine

Pathophysiology

The most common adult muscular dystrophy - an autosomal dominant, multisystem disorder in two forms, DM1 (a CTG trinucleotide repeat expansion in the DMPK gene) and DM2. The hallmark is myotonia:...

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