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Nemaline Myopathy

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated

Difficult AirwayVideo LaryngoscopeAspirationParalytic SensitivitySkeletal Muscle WeaknessAvoid OpioidsCareful PositioningAvoid HypothermiaPostoperative Ventilation Likely

Pathophysiology

Nemaline myopathy is a congenital myopathy named for the rod-shaped "nemaline" bodies seen in muscle fibers on biopsy, which derive from Z-disk and thin-filament protein. The causative mutations...

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