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Paramyotonia Congenita (PMC)

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated

Avoid HypothermiaAvoid SuccinylcholineHyperkalemiaSkeletal Muscle WeaknessAvoid StressorsAvoid Prolonged FastingUnstable ElectrolytesAvoid Lactated RingersArrhythmiasAvoid Neostigmine

Pathophysiology

Paramyotonia congenita (PMC) is a non-dystrophic myotonia caused by mutations in SCN4A, the gene for the skeletal muscle voltage-gated sodium channel. The same gene produces potassium-aggravated...

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