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Phencyclidine Use Disorder (PCP)

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated

HypertensionTachycardiaHyperthermiaSeizuresHypoglycemiaEmergence DeliriumRenal DysfunctionHyperkalemiaAvoid KetamineRhabdomyolysis

Pathophysiology

Phencyclidine (PCP) is a synthetic arylcycloalkylamine and a non-competitive NMDA receptor antagonist. It was developed as a general anesthetic in the 1950s and marketed as Sernyl, used surgically...

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