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Protein S Deficiency

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated

Blood Loss (Excessive)Careful PositioningOptimize HydrationDyspneaAnticoagulatedThrombosis Risk

Pathophysiology

Protein S is a vitamin K-dependent plasma glycoprotein. Roughly 40 percent circulates free and functionally active; the remaining 60 percent is bound to C4b-binding protein. Free protein S is the...

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