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Rett Syndrome (RTT)

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated

SeizuresArrhythmiasAspirationFull StomachAvoid OpioidsAvoid HypoxiaCareful PositioningBlood Loss (Excessive)AnemiaSkeletal Muscle WeaknessBone Fragility

Pathophysiology

Rett syndrome is an X-linked dominant neurodevelopmental disorder, lethal in hemizygous males, affecting roughly 1 in 10,000 to 15,000 females. About 90% to 95% carry a mutation in MECP2; atypical...

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