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Spinal Muscular Atrophy (SMA)

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated

AspirationFull StomachCopious SecretionsAvoid SuccinylcholineHyperkalemiaParalytic SensitivitySkeletal Muscle WeaknessCareful PositioningAvoid Prolonged FastingAvoid AcidosisDysglycemiaDelayed EmergenceHypoxiaBone FragilityPostoperative Ventilation LikelyRestrictive Lung DiseaseScoliosis

Pathophysiology

Spinal muscular atrophy (SMA) is an autosomal recessive degeneration of the anterior horn cells of the spinal cord that destroys alpha motor units, producing progressive proximal muscle weakness,...

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