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Substance Abuse - Cocaine

Anesthesia Implications

Clinically reviewed by anesthesia providers · Updated

Blood Loss (Excessive)Increased MACLabile Blood PressurePremature DeliveryReactive AirwayRefractory PainRenal AbnormalitiesTachycardia

Pathophysiology

Cocaine causes an increase in presynaptic release of catecholamines. Cocaine also blocks reuptake of norepinephrine , dopamine , and serotonin. Reduces production of nitric oxide. These affects...

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