Bronchospasm during general anesthesia is a critical event that requires prompt recognition and management. The classic manifestations include an expiratory wheeze, a drop in oxygen saturation, and difficulty in mechanical ventilation. Anesthetists should note that in severe cases, wheezing may be absent due to severely restricted airflow. A significant rise in ventilation pressures is typically observed, and widespread expiratory wheezing may be heard on auscultation or within the breathing circuit.
As bronchospasm progresses, the expiratory phase becomes prolonged, and carbon dioxide elimination is impaired, leading to a characteristic 'ramped' or 'shark-fin' appearance on the capnography waveform. This waveform pattern is a key indicator of bronchospasm and should alert the provider to the need for immediate intervention.

It is crucial to differentiate bronchospasm from other conditions that can mimic its presentation. Endobronchial intubation, where the endotracheal tube is inserted too far and into one bronchus, can cause similar signs. Likewise, if the tracheal tube tip is against the tracheal wall or mucous plugging is present, similar increased airway resistance and ventilation difficulties can closely resemble bronchospasm. These potential causes should be carefully excluded to ensure appropriate treatment.