Primary Name: Ginkgo (Ginkgo biloba)
Dosage: 120 to 240 mg/day for dementia; 120 to 160 mg/day for peripheral vascular disease (PVD).
Indications/Homeopathic Use
- Alzheimer’s disease
- Dementia
- Depression
- Improve overall brain function
- Arterial occlusive disease
- Attention-deficit hyperactivity disorder (ADHD)
- Reverse sexual dysfunction caused by selective serotonin reuptake inhibitors (SSRIs)
Perioperative Concerns:
The prolonged use of ginkgo before surgery can significantly elevate the risk of bleeding, especially when combined intraoperatively with other medications that inhibit platelet aggregation. Given ginkgo's influence on catecholamines, potential interactions may arise with MAOIs and SSRIs. Consequently, it is advisable to halt the use of ginkgo at least 36 hours before surgery. For patients using ginkgo to manage conditions such as dementia or depression, a gradual reduction over at least two weeks prior to surgery is recommended to safely taper off usage. Ginkgo has an active half-life ranging from 3 to 10 hours (Nagelhout & Plaus, 2023).
Additional Information
Ginkgo enhances cerebral blood flow and tissue perfusion by causing dilation of both arteries and veins. It also helps to prevent arterial spasms and reduces the permeability of capillaries. Additionally, ginkgo can decrease the aggregation of erythrocytes and blood viscosity, effects that may be attributed to prostaglandins or the vasoactive properties of catecholamines. It has the dual benefit of reducing clot formation and offering antioxidant protection. Furthermore, ginkgo supports mental functions by impacting nerve cells, which is likely due to an increase in alpha and 5HT receptors and a decrease in beta receptors. Side effects associated with ginkgo are generally mild but can include dizziness, gastrointestinal discomfort, headaches, and a risk of bleeding.
